The Estrogen Receptor α Signaling Pathway Controls Alternative Splicing in the Absence of Ligands in Breast Cancer Cells.
Jamal ElhasnaouiGiulio FerreroValentina MianoSantina CutrupiMichele De BortoliPublished in: Cancers (2021)
Our data supports the role of apoERα in maintaining the luminal phenotype of BC cells by extensively regulating gene expression at the alternative splicing level.
Keyphrases
- estrogen receptor
- induced apoptosis
- gene expression
- signaling pathway
- breast cancer cells
- cell cycle arrest
- pi k akt
- endoplasmic reticulum stress
- dna methylation
- multidrug resistant
- electronic health record
- oxidative stress
- epithelial mesenchymal transition
- big data
- machine learning
- cell death
- deep learning
- artificial intelligence
- data analysis