Predictive and Prognostic Significance of mRNA Expression and DNA Copies Aberrations of ERCC1 , RRM1 , TOP1 , TOP2A , TUBB3 , TYMS , and GSTP1 Genes in Patients with Breast Cancer.
Matvey M TsyganovMarina K IbragimovaEvgeniy Yu GarbukovIrina A TsydenovaKseniya A GaptulbarovaDaria S DolgashevaEkaterina A ZderevaAnastasia A FrolovaElena M SlonimskayaNikolai V LitvyakovPublished in: Diagnostics (Basel, Switzerland) (2022)
Thus, a complex assessment of the chemotherapy's gene expression is important not only for understanding the heterogeneity and molecular biology of breast cancer but also to obtain a more accurate disease prognosis.
Keyphrases
- gene expression
- single molecule
- dna methylation
- circulating tumor
- genome wide
- single cell
- copy number
- cell free
- dna repair
- locally advanced
- high resolution
- rectal cancer
- dna damage
- squamous cell carcinoma
- nucleic acid
- mass spectrometry
- young adults
- circulating tumor cells
- chemotherapy induced
- transcription factor
- breast cancer risk
- childhood cancer