Integration of a Cross-Ancestry Polygenic Model With Clinical Risk Factors Improves Breast Cancer Risk Stratification.
Placede T TshiabaDariusz K RatmanJiayi M SunTate S TunstallBrynn LevyPremal S ShahJeffrey N WeitzelMatthew RabinowitzAkash KumarKate M ImPublished in: JCO precision oncology (2023)
Adding a caPRS to the T-C model improves BC risk stratification for women of multiple ancestries, which could have implications for screening recommendations and prevention.