The relationship between pancreatic cancer and type 2 diabetes: the Fremantle Diabetes Study Phase I.

Published in: Internal medicine journal (2022)

Pancreatic cancer incidence was double (incidence rate ratio 2.06) in community-based adults with (n = 1291) versus without (n = 5158) type 2 diabetes followed for up to 25 years in the Fremantle Diabetes Study Phase 1. Sustained higher fasting plasma glucose reflecting insulin resistance and fewer comorbidities were statistically significant risk factors in the cohort with diabetes. Past pancreatitis was an aetiologically significant determinant in the cohort as a whole.

Keyphrases

type diabetes
glycemic control
insulin resistance
risk factors
cardiovascular disease
blood glucose
high fat diet
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
blood pressure
high fat diet induced