High dose psilocybin is associated with positive subjective effects in healthy volunteers.
Christopher R NicholasKelsey M HenriquezMichele C GassmanKaren M CooperDaniel MullerScott HetzelRandall T BrownNicholas V CozziChantelle ThomasPaul R HutsonPublished in: Journal of psychopharmacology (Oxford, England) (2018)
High doses of psilocybin elicited subjective effects at least as strong as the lower doses and resulted in positive persisting subjective effects 30 days after, indicating that a complete mystical experience was not a prerequisite for positive outcomes.