Genetic susceptibility to optic neuropathy in patients with alcohol use disorder.

Camille DelibesMarc FerréMarine RozetValérie Desquiret-DumasAlexis DescathaBénédicte GohierPhilippe GohierPatrizia Amati-BonneauDan MileaPascal Reynier

Published in: Journal of translational medicine (2024)

OCT can detect presence of asymptomatic optic neuropathy in patients with chronic alcohol use disorder. Furthermore, genetic susceptibility to optic neuropathy in this setting is found in almost a quarter of affected patients. Further studies may clarify the role of preventative measures in patients who might be predisposed to avoidable visual loss and blindness.

Keyphrases

alcohol use disorder
end stage renal disease
ejection fraction
genome wide
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
copy number
gene expression
optical coherence tomography
diabetic retinopathy
patient reported
case control
optic nerve