Diabetes, Associated Clinical Spectrum, Long-term Prognosis, and Genotype/Phenotype Correlations in 201 Adult Patients With Hepatocyte Nuclear Factor 1B (HNF1B) Molecular Defects.
Danièle Dubois-LaforgueErika CornuCécile Saint-MartinJoël CosteChristine Bellanné-ChantelotJosé Timsitnull nullPublished in: Diabetes care (2017)
In patients with HNF1B syndrome, diabetes complications, cardiovascular risk factors, CKD3-4, and ESRD are highly prevalent. At diabetes diagnosis, the presence of morphological and/or functional kidney disease may help etiological diagnosis. Genotype/phenotype correlations may have implications for the care and the prognosis of these patients.
Keyphrases
- nuclear factor
- cardiovascular risk factors
- end stage renal disease
- cardiovascular disease
- type diabetes
- chronic kidney disease
- toll like receptor
- glycemic control
- peritoneal dialysis
- ejection fraction
- healthcare
- newly diagnosed
- metabolic syndrome
- palliative care
- quality improvement
- skeletal muscle
- case report
- adipose tissue
- chronic pain
- weight loss
- affordable care act
- health insurance