Effect of Deep Brain Stimulation on Parkinson Disease Dementia: A Systematic Review and Meta-analysis.
Ali RazmkonSaeed AbdollahifardHirad RezaeiAmir Reza BahadoriParham EskandarzadehAmirAli Rastegar KazerooniPublished in: Basic and clinical neuroscience (2024)
Our results suggest that the STN-DBS group showed a larger cognitive decline than the patients receiving the best medical treatment (BMT). However, comparing STN-DBS with globus pallidus interna stimulation and pallidotomy could not demonstrate a significant statistical effect on the global dementia of patients. More long-term studies with larger sample sizes are needed to validate current findings.