The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia.

Shizuka SatoEiko YamamotoKaoru NiimiKazuhiko InoKimihiro NishinoShiro SuzukiTomomi KotaniHiroaki KajiyamaFumitaka Kikkawa

Published in: International journal of clinical oncology (2019)

The results suggest that the efficacy and the adverse effects of 4-day MEA for choriocarcinoma and high-risk GTN may be the same level as EMA/CO. However, further study will be needed for determining the criteria of changing the treatment regimen from 4-day MEA to the EA regimen.

Keyphrases

pregnant women
weight gain
high grade
oxidative stress
high dose
squamous cell carcinoma
locally advanced
physical activity
low dose
radiation therapy
birth weight
preterm birth
gestational age