Early-Onset Pancreatic Neuroendocrine Tumors: Clinical Presentation, Pathology Features, and Oncological Outcomes.

Alessandra PulvirentiHaley F HauserLaura M FiedlerCaitlin A McIntyreTiffany LeDiane L Reidy-LagunesKevin C SoaresVinod P BalachandranT Peter KinghamMichael I D'AngelicaJeffrey A DrebinWilliam R JarnaginNitya RajAlice C Wei

Published in: Annals of surgery (2023)

In this surgical cohort, we found that EO-PanNET is associated with hereditary syndromes but has pathological characteristics and oncological outcomes similar to LO-PanNET. These findings suggest that patients with EO-PanNET can be managed similarly to those with LO-PanNET.

Keyphrases

early onset
neuroendocrine tumors
late onset
rectal cancer
radical prostatectomy
prostate cancer
metabolic syndrome
adipose tissue
glycemic control
insulin resistance