Preoperative CA 19-9 Predicts Disease Progression in Colorectal Peritoneal Metastases Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Analysis from the US HIPEC Collaborative.

Nadege T FackcheRyan K SchmockerRichard NudotorBoateng KubiJordan M CloydTravis E GrotzKeith F FournierSean P DineenJula VeerapongJoel M BaumgartnerCallisia N ClarkeSameer H PatelGregory C WilsonLaura A LambertCourtney PokrzywaDaniel E AbbottByrne LeeCharles A StaleyMohammad Y ZaidiFabian M JohnstonJonathan B Greer

Published in: Annals of surgical oncology (2024)

Elevated CA 19-9 is associated with decreased PFS in patients with CRPM. While traditionally CEA is the main tumor marker assessed in colon cancer, we found that CA 19-9 may better inform preoperative risk stratification for poor oncologic outcomes in patients with CRPM. However, prospective studies are required to confirm this association.

Keyphrases

patients undergoing
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rectal cancer
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prostate cancer
radical prostatectomy
squamous cell carcinoma
type diabetes
case control
coronary artery disease
percutaneous coronary intervention