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Binge eating disorder.

Katrin Elisabeth GielCynthia M BulikFernando Fernandez-ArandaPhillipa HayAnna Keski-RahkonenKathrin SchagUlrike SchmidtStephan Zipfel
Published in: Nature reviews. Disease primers (2022)
Binge eating disorder (BED) is characterized by regular binge eating episodes during which individuals ingest comparably large amounts of food and experience loss of control over their eating behaviour. The worldwide prevalence of BED for the years 2018-2020 is estimated to be 0.6-1.8% in adult women and 0.3-0.7% in adult men. BED is commonly associated with obesity and with somatic and mental health comorbidities. People with BED experience considerable burden and impairments in quality of life, and, at the same time, BED often goes undetected and untreated. The aetiology of BED is complex, including genetic and environmental factors as well as neuroendocrinological and neurobiological contributions. Neurobiological findings highlight impairments in reward processing, inhibitory control and emotion regulation in people with BED, and these neurobiological domains are targets for emerging treatment approaches. Psychotherapy is the first-line treatment for BED. Recognition and research on BED has increased since its inclusion into DSM-5; however, continuing efforts are needed to understand underlying mechanisms of BED and to improve prevention and treatment outcomes for this disorder. These efforts should also include screening, identification and implementation of evidence-based interventions in routine clinical practice settings such as primary care and mental health outpatient clinics.
Keyphrases
  • primary care
  • mental health
  • clinical practice
  • physical activity
  • weight loss
  • type diabetes
  • healthcare
  • metabolic syndrome
  • gene expression
  • skeletal muscle
  • dna methylation
  • childhood cancer