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Local and distant tumor dormancy during early stage breast cancer are associated with the predominance of infiltrating T effector subsets.

Hussein F AqbiCara ColemanMelika ZareiSaeed H ManjiliLaura GrahamJennifer KoblinskiChunquing GuoYibin XieGeorgi GuruliHarry D BearMichael O IdowuMehran HabibiXiang-Yang WangMasoud H Manjili
Published in: Breast cancer research : BCR (2020)
Our results suggest that immunotherapeutic targeting of semi-allogeneic mutant neoantigens during tumor dormancy might prevent distant recurrence of the disease.
Keyphrases
  • early stage
  • lymph node
  • stem cell transplantation
  • bone marrow
  • dendritic cells
  • peripheral blood
  • squamous cell carcinoma
  • young adults
  • radiation therapy
  • immune response
  • free survival
  • type iii