Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage.
Lays Fernanda Nunes DouradoFlavia Rodrigues da SilvaCibele Rodrigues ToledoCarolina Nunes da SilvaCleildo Pereira SantanaBruna Lopes da CostaMaria Elena de LimaArmando da Silva Cunha JuniorPublished in: The journal of venomous animals and toxins including tropical diseases (2020)
The intraocular administration of these peptides was well tolerated and presented protective activity against retinal degeneration, suggesting the potential use of these peptides as neuroprotectors in the ophthalmological field.