Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia.

Masahito SawahataDaisuke MoriYuko AriokaHisako KuboItaru KushimaKanako KitagawaAkira SobueEmiko ShishidoMariko SekiguchiAkiko KodamaRyosuke IkedaBranko AleksicHiroki KimuraKanako IshizukaTaku NagaiKozo KaibuchiToshitaka NabeshimaKiyofumi YamadaNorio Ozaki

Published in: Psychiatry and clinical neurosciences (2020)

The present results in novel Reln-del mice modeled after our patient with a novel exonic deletion in RELN are expected to contribute to the development of reelin-based therapies for schizophrenia.

Keyphrases

bipolar disorder
mouse model
case report
type diabetes
high fat diet induced
adipose tissue
metabolic syndrome
insulin resistance
wild type