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Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial.

Joanna M ShepherdJennifer RossLourdes AntonClaire RourkeAdam R BrentnallJoel TarningNicholas J WhiteChristoph ThiemermannKarim Brohi
Published in: Intensive care medicine (2023)
Among critically ill trauma patients, artesunate is unlikely to improve organ dysfunction and might be associated with a higher VTE rate.
Keyphrases
  • trauma patients
  • venous thromboembolism
  • spinal cord injury
  • oxidative stress
  • antiretroviral therapy