Caveolin-1 influences epithelial collective cell migration via FMNL2 formin.
Hiroko Katsuno-KambeRobert G PartonAlpha S YapJessica L TeoPublished in: Biology of the cell (2020)
Although epithelial collective cell migration has been observed in multiple contexts both in vivo and in vitro, the inherent coupling and coordination of activity between cells within the monolayer remain incompletely understood. Our study highlights a role for CAV1 in regulating intraepithelial motility, an effect that involves the formin FMNL2.