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Caveolin-1 influences epithelial collective cell migration via FMNL2 formin.

Hiroko Katsuno-KambeRobert G PartonAlpha S YapJessica L Teo
Published in: Biology of the cell (2020)
Although epithelial collective cell migration has been observed in multiple contexts both in vivo and in vitro, the inherent coupling and coordination of activity between cells within the monolayer remain incompletely understood. Our study highlights a role for CAV1 in regulating intraepithelial motility, an effect that involves the formin FMNL2.
Keyphrases
  • cell migration
  • induced apoptosis
  • high grade
  • cell cycle arrest
  • endoplasmic reticulum stress
  • biofilm formation
  • cell death
  • staphylococcus aureus