Epidermal T cell subsets-Effect of age and antigen exposure in humans and mice.

Anne-Sofie Østergaard GadsbøllMia Hamilton JeeMalin Glindvad AhlströmBeatrice Dyring-AndersenAnders WoetmannNiels ØdumJeanne Duus JohansenCarsten GeislerCharlotte Menné Bonefeld

Published in: Contact dermatitis (2021)

Taken together, we show that antigen exposure, as opposed to age, is the major factor determining the composition of epidermal T cells, suggesting that the skin of antigen-experienced mice better reflects the immunological conditions in human skin.

Keyphrases

wound healing
high fat diet induced
type diabetes
metabolic syndrome
insulin resistance
adipose tissue
soft tissue
wild type