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Limited impact of impaired awareness of hypoglycaemia and severe hypoglycaemia on the inflammatory profile of people with type 1 diabetes.

Namam AliAnna W M JanssenMartin JaegerLisa Van de WijerWouter van der HeijdenRob Ter HorstPriya VartAlain van GoolLeo A B JoostenMihai G NeteaRinke StienstraBastiaan E De GalanCornelis Cees J Tack
Published in: Diabetes, obesity & metabolism (2020)
IAH or history of SH in people with type 1 diabetes was not associated with altered inflammatory profiles, arguing against chronically elevated inflammatory activity mediating the increased cardiovascular risk associated with hypoglycaemia. The finding of higher circulating concentrations of IL-18BP in individuals with a history of SH requires further investigation.
Keyphrases
  • type diabetes
  • oxidative stress