Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176.

Mickey Konings Bert Gerrits van den Ende Mirthe W J Raats Ahmed Hassan Fahal Wendy van de Sande Ferry Hagen

Published in: Mycopathologia (2024)

Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.

Keyphrases

binding protein
gene expression
dna binding
small molecule
single cell
adverse drug
electronic health record