Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats.
Boris L ZybailovGalina V GlazkoYasir RahmatallahDmitri S AndreyevTaylor McElroyOleg KaradutaStephanie D ByrumLisa OrrAlan J TackettSamuel G MackintoshRicky D EdmondsonDorothy A KiefferR J MartinSean H AdamsNosratola D VaziriJohn M ArthurPublished in: PloS one (2019)
Metaproteomics analysis of cecum contents of CKD rats with and without resistant starch supplementation reveals changes within gut microbiota at unprecedented resolution, providing both functional and taxonomic information. Proteins and organisms differentially abundant with RS supplementation point toward a shift from mucin degraders to butyrate producers.