Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes.

Bin-Jia Sun Rong-Mei PengQing LuJing Hong

Published in: Journal of ophthalmology (2019)

GCV intravitreal injection offers effective, sustained drug concentration in the anterior chamber, and its damage to retina receded over time. Intracameral injection results in rapid drug elimination and severe damage to endothelium and thus is not recommended.

Keyphrases

optical coherence tomography
diabetic retinopathy
cataract surgery
oxidative stress
ultrasound guided
optic nerve
nitric oxide
drug induced
vascular endothelial growth factor
emergency department
early onset
adverse drug
wound healing
endothelial cells
loop mediated isothermal amplification