Association of glutathione-S-transferase p1 gene promoter methylation and the incidence of prostate cancer: a systematic review and meta-analysis.

Xueliang ZhouDechao JiaoMengmeng DouJianjian ChenZhaonan LiYahua LiJuanfang LiuXinwei Han

Published in: Journal of cancer research and clinical oncology (2019)

Methylation of the GSTP1 promoter may increase the risk of prostate cancer. This study may provide a strategic direction for prostate cancer research. Pending validation of these findings, the methylation of the GSTP1 promoter may be a potential biomarker to diagnose prostate cancer.

Keyphrases

prostate cancer
dna methylation
radical prostatectomy
genome wide
gene expression
transcription factor