NHP BurkPx: A multiplex serodiagnostic bead assay to monitor Burkholderia pseudomallei exposures in non-human primates.

Kimberly R CelonaAustin B ShannonDerek SondereggerJinhee YiFernando P MonroyChristopher AllenderHeidie HornstraMary B BarnesElizabeth S DidierRudolf P BohmKathrine Phillippi-FalkensteinDaniel SanfordPaul KeimErik W Settles

Published in: PLoS neglected tropical diseases (2023)

We employed a previously standardized assay for humans, the BurkPx assay, and assessed its diagnostic potential for detection of B. pseudomallei exposure in NHP. The assay is expected to be useful for surveillance in NHP colonies, in investigations of suspected accidental releases or exposures, and for identifying vaccine correlates of protection.

Keyphrases

high throughput
air pollution
endothelial cells
public health
pulmonary embolism
real time pcr
risk assessment
induced pluripotent stem cells
human health