Immune Checkpoint Inhibitor-Induced Myositis/Myocarditis with Myasthenia Gravis-like Misleading Presentation: A Case Series in Intensive Care Unit.
François DeharoJulien CarvelliJennifer CautelaMaxime GarciaClaire SarlesAndre Maues de PaulaJérémy BourenneMarc GainnierAmandine BichonPublished in: Journal of clinical medicine (2022)
These cases highlight the lack of knowledge of irAEs among physicians, aggravated by misleading overlapping forms, requiring specific management in trained units and multidisciplinary care. Severe MG-like presentation of irAEs constitutes an absolute therapeutic emergency with high-dose corticosteroids and targeted immunosuppressive therapy.
Keyphrases
- myasthenia gravis
- intensive care unit
- high dose
- healthcare
- quality improvement
- primary care
- high glucose
- emergency department
- public health
- drug induced
- low dose
- case report
- palliative care
- diabetic rats
- mechanical ventilation
- stem cell transplantation
- early onset
- cancer therapy
- resistance training
- affordable care act
- oxidative stress
- mesenchymal stem cells
- bone marrow
- rheumatoid arthritis
- health insurance