SOX2OT lncRNA Inhibition Suppresses the Stemness Characteristics of Esophageal Tumorspheres.

Boshra HaghiMarie Saghaeian JaziAyyoob KhosraviSeyyed Mehdi JafariJahanbakhsh Asadi

Published in: Non-coding RNA (2022)

Altogether our results showed the regulatory role of SOX2OT in pluripotency and stemness in ESCC tumorspheres. Our results suggest a potential application of SOX2OT inhibition in combination with docetaxel for ESCC inhibition in vitro.

Keyphrases

stem cells
transcription factor
signaling pathway
squamous cell carcinoma