Correlation between copper speciation and transport pathway in Caco-2 cells.

Min WuCong WangLeqin KeDewen ChenYumei Qin Jianzhong Han

Published in: Journal of the science of food and agriculture (2022)

These results indicate that the intracellular accumulation of copper derived from copper ion and copper complex is mediated by distinct copper transport pathways. Copper speciation may be an important factor that affects copper absorption and toxicity. © 2022 Society of Chemical Industry.

Keyphrases

oxide nanoparticles
induced apoptosis
oxidative stress
cell proliferation
reactive oxygen species
endoplasmic reticulum stress