Radiosurgery and Stereotactic Brain Radiotherapy with Systemic Therapy in Recurrent High-Grade Gliomas: Is It Feasible? Therapeutic Strategies in Recurrent High-Grade Gliomas.

Fabiana GregucciAlessia SurgoRoberta CarbonaraLetizia LaeraMaria Paola CilibertiMaria Annunziata GentileMorena CaliandroNicola SassoIlaria BonaparteVincenzo FanelliRomina TortoraEleonora PaulicelliGiammarco SuricoGiuseppe Lombardi Francesco Signorelli Alba Fiorentino

Published in: Journal of personalized medicine (2022)

Re-RT with SRT/FSRT in association with second-line systemic therapy is a safe and feasible treatment for patients with HGG recurrence. Validation of these results by prospective studies is needed.

Keyphrases

high grade
low grade
brain metastases
early stage
radiation therapy
white matter
small cell lung cancer
squamous cell carcinoma
resting state
stem cells
combination therapy
blood brain barrier
case control
clinical evaluation