Irritable Bowel Syndrome Is Not Associated with an Increased Risk of Polyps and Colorectal Cancer: A Systematic Review and Meta-Analysis.

Theodoros VichosAli RezaiePetros VichosBrooks CashMark Pimentel

Published in: Digestive diseases and sciences (2023)

Our analyses reveal a decreased incidence of colorectal polyps in IBS, although CRC did not reach significance. Mechanistic studies with detailed genotypic analysis and clinical phenotyping are needed to better elucidate the potentially protective effect of IBS on CRC development.

Keyphrases

irritable bowel syndrome
chronic rhinosinusitis
risk factors
genome wide
high throughput
single cell
gene expression
case control