Pediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction.
David F ColónCarlos W WanderleyWalter M TuratoVanessa F BorgesMarcelo FranchinFernanda V S CastanheiraDaniele NascimentoDouglas PradoMikhael Haruo Fernandes de LimaLeila C VolponSilvia K KavagutiAna P CarlottiFabio CarmonaBernardo S FranklinThiago M CunhaJosé Carlos Alves FilhoFernando de Queiroz CunhaPublished in: British journal of pharmacology (2023)
These findings demonstrate a crucial and age-dependent role for IL-33 in post-sepsis immunosuppression. Thus, a better understanding of this process could lead to differential treatments for adult and pediatric sepsis.