Prothrombotic state in patients with stable COPD: an observational study.

Christos KyriakopoulosChristos ChronisEvaggelia PapapetrouAthina TatsioniKonstantina GartzonikaChristina TsaousiAthena GogaliChristos KatsanosAikaterini VaggeliCharikleia TselepiGeorgios DaskalopoulosStavros KonstantopoulosKonstantinos Kostikas Athanasios K Konstantinidis

Published in: ERJ open research (2021)

Patients with stable COPD exhibited increased levels of key coagulation factors and decreased levels of coagulation inhibitors, namely protein S and antithrombin, compared to COPD-free smokers. Among COPD patients, increased levels of FII, FV and FX and decreased levels of protein S were found in patients with more severe disease.

Keyphrases

chronic obstructive pulmonary disease
lung function
end stage renal disease
newly diagnosed
ejection fraction
peritoneal dialysis
prognostic factors
smoking cessation
early onset
amino acid
patient reported outcomes
patient reported