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Targeting POLD1 to suppress the proliferation and migration of breast cancer MDA-MB-231 cell lines by downregulation of SIRT1.

Areege Ibrahim SalihBasma Talib Al-SudaniBahir Abdul-Razzaq Mshimesh
Published in: Toxicology research (2024)
SIRT1 could have an oncogenic role in breast cancer development and progression via activating POLD1. These conclusions present new insights into the underlying mechanisms of TNBC.
Keyphrases
  • signaling pathway
  • oxidative stress
  • ischemia reperfusion injury
  • cell proliferation
  • transcription factor
  • breast cancer cells