Substrate Specific Metal-Ligand Cooperative Binding: Considerations for Weak Intramolecular Lewis Acid/Base Pairs.

John J KiernickiEmily E NorwineMatthias Zeller Nathaniel K Szymczak

Published in: Inorganic chemistry (2021)

Metal-ligand cooperative binding modes were interrogated in a series of zinc bis(thiophenoxide) complexes. A weak B-S binding interaction is observed in solution between the weakly Lewis basic thiophenoxide ligands and an appended trialkylborane. The energy of this binding event is dependent upon the strength of the Lewis acid and its proximity to the zinc thiophenoxide.

Keyphrases

dna binding
binding protein
transcription factor
ionic liquid