Association of CD8 T cell apoptosis and EGFR mutation in non-small lung cancer patients.
Chao ZhaoChunxia SuXuefei LiCaicun ZhouPublished in: Thoracic cancer (2020)
Non-small cell lung cancer EGFR mutation could promote CD8 T cell apoptosis more than wild-type. Inhibiting CD8 + TILs apoptosis may strengthen immunotherapy effects in EGFR-mutant NSCLC patients.
Keyphrases
- small cell lung cancer
- end stage renal disease
- oxidative stress
- ejection fraction
- newly diagnosed
- chronic kidney disease
- wild type
- endoplasmic reticulum stress
- cell death
- tyrosine kinase
- peritoneal dialysis
- cell cycle arrest
- prognostic factors
- signaling pathway
- advanced non small cell lung cancer
- patient reported
- pi k akt