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Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment.

Md Anayet HasanMd Habibul Hasan MazumderAfrin Sultana ChowdhuryAmit DattaMd Arif Khan
Published in: Source code for biology and medicine (2015)
This predicted structure of Pftk will serve first hand in the future development of effective Pftk inhibitors with potential anti-malarial activity. However, this is a preliminary study of designing an inhibitor against Plasmodium falciparum 3D7; the results await justification by in vitro and in vivo experimentations.
Keyphrases
  • plasmodium falciparum
  • molecular docking
  • molecular dynamics simulations
  • current status
  • emergency department
  • combination therapy
  • human health