The TCN2 variant of rs9606756 [Ile23Val] acts as risk loci for obesity-related traits and mediates by interacting with Apo-A1.

Prashantha HebbarFadi AlkayalRasheeba NizamMotasem MelhemNaser ElkumSumi Elsa JohnMohamed Abu-FarhaOsama AlsmadiThangavel Alphonse Thanaraj

Published in: Obesity (Silver Spring, Md.) (2017)

The TCN2 variant acts as a risk factor for WC in the Arab population. The variant mediates obesity-related anthropometric traits via interactions with Apo-A1/high-density lipoprotein or TP53.

Keyphrases

high density
genome wide
insulin resistance
metabolic syndrome
weight loss
type diabetes
weight gain
high fat diet induced
body composition
dna methylation
adipose tissue
skeletal muscle
body mass index
drug induced
genome wide association study
low density lipoprotein