Improved survival of viral hepatocellular carcinoma but not non-viral hepatocellular carcinoma from 2000 to 2020: A multi-centre cohort study of 6007 patients from high-volume academic centres in Japan.
Hidenori ToyodaKazuya KariyamaAtsushi HiraokaKunihiko TsujiToru IshikawaTakeshi HatanakaAtsushi NaganumaSatoshi YasudaKazuhiro NousoSatoru KakizakiTakashi KumadaHamish InnesPhilip James JohnsonPublished in: Alimentary pharmacology & therapeutics (2022)
The prevalence of non-viral HCC is increasing. Although the survival of patients with viral HCC improved significantly over the past two decades, there was no improvement in patients with non-viral HCC. This was presumably due mainly to lower surveillance among patients with non-viral HCC and failure to diagnose early-stage HCC.