Selective Opioid Antagonists Following Bowel Resection for Prevention of Postoperative Ileus: a Systematic Review and Meta-analysis.
Tyler McKechnieTharani AnpalaganSimarpreet IchhpunianiYung LeeKarim RamjiCagla EskiciogluPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2021)
Rate of POI decreases with the use of selective opioid antagonists in patients undergoing bowel resection. Selective opioid antagonists also improve LOS, rates of readmission, and 30-day morbidity for patients undergoing open bowel resection. Addition of these medications to enhance recovery after surgery protocols should be considered.