Genetic screening of Chinese patients with hydatidiform mole by whole-exome sequencing and comprehensive analysis.

Jingyi YangLiying YanRong LiPing LiuJie QiaoYan LiuXu Zhi

Published in: Journal of assisted reproduction and genetics (2022)

Our study enriched the spectrum of variants in NLRP7 and KHDC3L in Chinese HM patients and provided a new outlook on the effects of heterozygous variants in KHDC3L. The novel candidate genetic variants associated with HMs reported in this study will also contribute to further research on HMs.

Keyphrases

copy number
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
early onset
genome wide
dna methylation
patient reported outcomes
patient reported