Atrase B, a novel metalloprotease with anti-complement and anti-coagulant activity, significantly delays discordant cardiac xenograft rejection.
Cheng FuLei ShiXia HuangHao FengXiaosheng TanSong ChenLan ZhuQianyun SunGang ChenPublished in: Xenotransplantation (2020)
The dual activities of anti-complement and anti-coagulation make atrase B a potential adjuvant therapeutic drug for use in xenotransplantation.