Implementation of an NGS panel for clinical practice in paraffin-embedded tissue samples from locally advanced and metastatic melanoma patients.
Paola CastilloMarta MarginetPedro JaresMireia GarcíaElena GonzalvoAna M AranceAdriana GarcíaLlúcia AlósCristina TeixidóPublished in: Exploration of targeted anti-tumor therapy (2020)
Targeted-NGS testing is a feasible technique to implement in the routine clinical practice. Based on our results, NGS has provided more information on target-genes than RT-PCR technique, maximizing the benefit for patients with advanced melanoma.
Keyphrases
- clinical practice
- locally advanced
- end stage renal disease
- ejection fraction
- squamous cell carcinoma
- newly diagnosed
- healthcare
- primary care
- peritoneal dialysis
- genome wide
- rectal cancer
- radiation therapy
- neoadjuvant chemotherapy
- prognostic factors
- gene expression
- transcription factor
- patient reported
- skin cancer
- phase ii study
- genome wide identification