Care of the critically ill neonate with hypoxemic respiratory failure and acute pulmonary hypertension: framework for practice based on consensus opinion of neonatal hemodynamics working group.
Amish JainRegan E GiesingerShyamala DakshinamurtiYasser ElSayedRobert P JankovDany E WeiszSatyan LakshminrusimhaSouvik MitraMjaye L MazwiJoseph TingMichael NarveyPatrick J McNamaraPublished in: Journal of perinatology : official journal of the California Perinatal Association (2022)
Circulatory transition after birth presents a critical period whereby the pulmonary vascular bed and right ventricle must adapt to rapidly changing loading conditions. Failure of postnatal transition may present as hypoxemic respiratory failure, with disordered pulmonary and systemic blood flow. In this review, we present the biological and clinical contributors to pathophysiology and present a management framework.
Keyphrases
- respiratory failure
- pulmonary hypertension
- blood flow
- extracorporeal membrane oxygenation
- pulmonary artery
- mechanical ventilation
- healthcare
- pulmonary arterial hypertension
- acute respiratory distress syndrome
- quality improvement
- palliative care
- preterm infants
- clinical practice
- intensive care unit
- pain management
- coronary artery
- pregnant women
- congenital heart disease