Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model.

Ashley JahnCharlie BodreauKate FarthingFawzy A Elbarbry

Published in: European journal of drug metabolism and pharmacokinetics (2018)

It does not appear that intermittent bolus administration of intravenous benzodiazepines for alcohol withdrawal influenced renal function or anion gap regardless of number of administered doses, amount of PG received, or the estimated PG concentration.

Keyphrases

high dose
alcohol consumption
oxidative stress
ionic liquid
high intensity