Computed Tomography-Based Body Composition Is Not Consistently Associated with Outcome in Older Patients with Colorectal Cancer.
Stéphanie M L M LooijaardCarel G M MeskersMonique S Slee-ValentijnDonald E BoumanA N Machteld WymengaJoost M KlaaseAndrea Britta MaierPublished in: The oncologist (2019)
Computed tomography (CT)-based body composition, including muscle mass, muscle density, and intermuscular, visceral, and subcutaneous adipose tissue, showed inconsistent and nonsignificant associations with surgery-related complications, dose-limiting toxicity, and overall survival in older adults with colorectal cancer. This study underscores the need to verify whether CT-based body composition measures are worth implementing in clinical practice.
Keyphrases
- body composition
- computed tomography
- dual energy
- image quality
- positron emission tomography
- contrast enhanced
- adipose tissue
- resistance training
- bone mineral density
- clinical practice
- insulin resistance
- magnetic resonance imaging
- physical activity
- community dwelling
- middle aged
- minimally invasive
- skeletal muscle
- coronary artery bypass
- oxidative stress
- high fat diet
- magnetic resonance
- metabolic syndrome
- surgical site infection
- quality improvement
- postmenopausal women
- acute coronary syndrome