Electrochemical Phenyl-Carbonyl Coupling Reaction of Aromatic Aldehydes or Ketones.

Zenghui ZhangHaiyang WangJinhua ZhengXiao YuFusheng LiuJinbo ZhaoYi LiuMei ZhangCheng-Cai XiaJuan Cao

Published in: The Journal of organic chemistry (2023)

An electrochemical phenyl-carbonyl coupling reaction of aromatic aldehydes or ketones to synthesize 4-(hydroxy(phenyl)methyl)benzaldehyde derivatives has been developed. The method shows high chemoselectivity, broad functional group compatibility, atom economy, and environmental benignity and has good potential applicability.

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