A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome.

Megan S BradleyEmily E BurkeCarole GrenierCindy L AmundsenSusan K MurphyNazema Y Siddiqui

Published in: Neurourology and urodynamics (2018)

The results demonstrate the feasibility of using voided urine specimens from women with IC/BPS to perform DNA methylation assessments. Additionally, the data suggest genes within or downstream of the MAPK pathway exhibit altered methylation in IC/BPS.

Keyphrases

dna methylation
genome wide
gene expression
copy number
signaling pathway
spinal cord injury
oxidative stress
electronic health record
machine learning
pi k akt
cell proliferation
artificial intelligence