Hematological, inflammatory and serological responses among COVID-19 patients admitted to intensive care unit.
Mirette A MorganSarra E SalehAzza H SalamoniMohammad Y AlshahraniKhaled M A AboshanabPublished in: Future science OA (2024)
Aim: To correlate hematological, inflammatory indicators and serological responses among COVID-19 patients to point out the significant biomarkers for disease management and prognosis. Materials & methods: Standard analytical and molecular methods were used to assess various inflammatory and serological Responses among COVID-19 patients (ICU- (n = 99) and non-ICU patients (n = 64) as compared with health control (n = 40). Results: Significant differences in the Hb, WBC, Lymphocyte count, CRP and serum ferritin ( p < 0.05) were observed. Patients' IgM/IgG antibodies against SARS-CoV-2 were associated with increased CRP, LDH and serum ferritin levels. Conclusion: A significant association between serum IgG/IgM and ICU admission was observed. Although serum ferritin and LDH can offer information about the extent of inflammation, they are exclusive factors for ICU admission.
Keyphrases
- intensive care unit
- sars cov
- end stage renal disease
- ejection fraction
- oxidative stress
- mechanical ventilation
- newly diagnosed
- emergency department
- chronic kidney disease
- public health
- peritoneal dialysis
- healthcare
- coronavirus disease
- mental health
- patient reported outcomes
- risk assessment
- single molecule
- peripheral blood
- social media
- mass spectrometry
- patient reported
- acute respiratory distress syndrome