A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Patients with Bladder Cancer.
Vinata B LokeshwarDaley S MoreraSarrah L HasanaliTravis J YatesMarie C HupeJudith KnappSoum D LokeshwarJiaojiao WangMartin J P HennigRohitha BaskarDiogo O EscuderoRonny R RacineNeetika DhirAndre R JordanKelly HoyeIjeoma AzihMurugesan ManoharanZachary KlaassenSravan KavuriLuis E LopezSantu GhoshBal L LokeshwarPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Our study discovered the first naturally-occurring eukaryotic/human Chase and connected it to disease pathology, specifically cancer. V1-Chase is a driver of malignant bladder cancer and potential predictor of outcome in patients with bladder cancer.