The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes.

Bingbing ChengChenchen BingRobert M StaruchSumbul ShaikhMichelle Wodzak StaruchDebra SzczepanskiNoelle S WilliamsTheodore W LaetschRajiv Chopra

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2021)

Conclusions: These results provide guidance on clinical protocol design of hyperthermia-triggered drug delivery.

Keyphrases

drug delivery
cancer therapy
drug release
left ventricular
high intensity
heart failure
contrast enhanced
atrial fibrillation