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Pacritinib and concurrent azole antifungal therapy is deliverable in patients with hematologic malignancies.

Dina TrangDat NgoHaris AliJose Tinajero
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2024)
This is the first clinical experience describing concurrent pacritinib and azole antifungals. Our experience shows that in the setting where this interaction cannot be avoided, concurrent administration is feasible with close monitoring and possible empiric dose reductions in select patients.
Keyphrases
  • candida albicans
  • end stage renal disease
  • locally advanced
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • peritoneal dialysis
  • prognostic factors
  • squamous cell carcinoma
  • stem cells
  • rectal cancer